From Rybelsus to Mounjaro: Dr. Nivedita Dadu's Honest Weight Loss Journey

From Rybelsus to Mounjaro: Dr. Nivedita Dadu's Honest Weight Loss Journey
Dr. Nandini Dadu | July 31, 2026

Most weight loss advice comes from people who haven't actually lived through the frustration of trying everything and still not seeing lasting results. That's what makes this conversation different. Dr. Nivedita Dadu, who has personally struggled with weight for years, walked through her entire journey years of diets, two other GLP-1 medications, and eventually Mounjaro before finding what genuinely worked. If you're considering a weight loss treatment in Delhi and want an honest, doctor's-eye account rather than a marketing pitch, this is worth reading in full.

A Familiar Struggle: Years of Trying and Restarting

Dr. Dadu described herself as someone who has always been overweight, having tried several diets over the years, including intermittent fasting. The problem wasn't lack of effort, it was sustainability. A hectic schedule made it hard to stick to any single approach for long, and plateaus would set in just when things seemed to be working, leading to frustration and eventual giving up. Being self-described as "a foodie" and an emotional eater added another layer of difficulty, creating a familiar cycle: lose some weight, regain it, restart, repeat.

The First Attempt: Rybelsus

Before considering Mounjaro, Dr. Dadu tried Rybelsus, the oral form of semaglutide available in India at the time (since Ozempic itself wasn't available domestically). She started at a low 7 mg dose and gradually increased to 14 mg. While she did see some results, the experience wasn't a good one. Persistent nausea made it difficult to focus on work, and the daily discipline required to take the tablet became genuinely stressful. Eventually, the nausea outweighed the benefits, and she made the call to stop.

A Detour Through Anti-Inflammatory Diets

Around the same time, anti-inflammatory diets were gaining popularity, partly fueled by celebrity claims of dramatic results. Dr. Dadu researched the approach thoroughly and did try incorporating it, cutting processed foods, reducing high-carb intake, and adding more legumes, berries, nuts, and healthy fats to her diet. While she acknowledged it's a genuinely healthy, sustainable lifestyle change, it simply wasn't fast enough for someone needing to lose a significant amount of weight. It worked well as a supporting habit, but not as a primary weight loss strategy on its own.

What Dr. Dadu Tried Before Mounjaro

Approach

Key Outcome

Intermittent Fasting

Difficult to sustain due to hectic schedule

Rybelsus (Semaglutide tablets)

Effective but caused significant nausea

Anti-Inflammatory Diet

Healthy long-term habit, too slow for major weight loss

Victoza (Liraglutide)

Better tolerated, but hit a ceiling effect early

Victoza and the Ceiling Effect

Next came Victoza, a daily liraglutide injection that had been available in India for a while. Dr. Dadu found her experience with Victoza considerably better than Rybelsus, with no notable side effects and steady early progress. The issue, however, was a ceiling effect once the dose reached its maximum, weight loss plateaued around 6-8 kg with no further scope to increase dosage. For someone needing to lose considerably more, this became a limiting factor rather than a long-term solution.

Why Mounjaro Over Ozempic?

With Ozempic gaining massive international popularity, extensive research became necessary both as a doctor now offering GLP-1 treatments at her clinic and as a patient herself. A few clear findings shaped the decision. Ozempic wasn't officially available in India, only through unofficial channels. Studies also showed Ozempic typically supports around 6-7% body weight reduction, while Mounjaro can support up to 20%. Additionally, Mounjaro carries FDA approval specifically for weight loss, with comparatively lower reported side effects than Ozempic.

Ozempic vs Mounjaro Key Differences Considered

Factor

Ozempic

Mounjaro

Availability in India

Not officially available

Available

Average Weight Loss

6-7% of body weight

Up to 20% of body weight

FDA Approval for Weight Loss

Not approved for this use

Approved

Side Effect Profile

Slightly higher

Comparatively lower

Starting Mounjaro: The Dosing Decision

Given her prior experience with Rybelsus and Victoza, Dr. Dadu skipped the standard 2.5 mg starting dose and began at 5 mg, since her body was already somewhat conditioned to GLP-1 medications. This is something she was clear shouldn't be replicated by patients without medical guidance. Dosing decisions like this depend entirely on individual history and require a doctor's supervision, not self-adjustment.

She stayed on 5 mg for about a month to six weeks with no side effects and steady progress, before moving to 7.5 mg the dose she remained on longest, for roughly three and a half months, during which the bulk of her weight loss occurred. Her approach was deliberately unhurried: rather than rushing toward higher doses, she prioritized getting results at the lowest effective dose.

Supporting the Journey: IV Drips and Aesthetic Treatments

Throughout this period, Dr. Dadu received IV drips every two to three weeks containing collagen, glutathione, vitamins, and NAC, alongside her Mounjaro doses. She reported zero side effects during her longest stretch on 7.5 mg, something she partly attributes to this nutritional support alongside the medication.

She was equally candid about aesthetic support during weight loss continuing hair treatments due to past PCOS-related thinning, facial treatments for hydration and glow, masseter Botox for facial contouring, and body contouring devices to prevent sagging skin. Her point was clear: past a certain age, skincare and body maintenance require more than diet alone, given hormonal shifts, rising stress levels, and environmental factors that come with time.

Supporting Treatments Alongside Mounjaro

Treatment

Purpose

IV Drips (Collagen, Glutathione, NAC)

Nutritional support, reduced side effects

Hair Treatments

Managing PCOS-related thinning

Facial Hydration Treatments

Maintaining skin glow during weight loss

Masseter Botox

Facial contouring

Body Contouring Devices

Preventing skin sagging

Beyond Weight Loss: What Patients Are Actually Experiencing

Dr. Dadu shared that a large share of her patients dealing with PCOS come in with adult acne, unwanted facial hair, and hair thinning often without realizing an underlying hormonal cause. Another common group presents with acanthosis nigricans, causing dark pigmentation around the neck, underarms, and thighs. She described one patient whose acanthosis cleared visibly after just two Mounjaro doses, even with only 2 kg lost so far a clear sign that GLP-1 treatment works on multiple health markers, not weight alone.

Her broader point was that Mounjaro (and GLP-1 medications generally) shouldn't be viewed purely as weight loss drugs. They support better metabolism, reduce inflammation, improve insulin resistance, and help preserve lean muscle mass making the body a genuinely healthier version of itself in multiple ways.

Why Doctor Supervision Matters

Dr. Dadu was firm that starting Mounjaro without medical guidance carries real risks. Baseline blood tests, checking for contraindications, and regular monitoring every four to six weeks are essential to catch nutritional deficiencies early and track thyroid, liver, and kidney function. This is exactly the kind of oversight doctors in Delhi with experience in GLP-1 protocols provide, and it's what allows for maximum results with minimal side effects at the lowest effective dose.

If you're considering this route yourself, it's worth having a proper consultation rather than starting on your own, particularly given how individual factors like prior medication history and baseline health affect the right approach. Clinics like Dadu Medical Centre combine GLP-1 treatment with nutritionist support and IV formulations to build a customized, medically supervised plan.

Frequently Asked Questions

01. Why did Dr. Dadu choose Mounjaro over Ozempic?
Mounjaro is FDA-approved for weight loss, supports greater weight reduction, and had fewer reported side effects compared to Ozempic.
02. Can I start Mounjaro at a higher dose like 5 mg?
Only under medical supervision starting dose depends on individual history and should never be self-decided.
03. Does Mounjaro cause a plateau like other medications?
Dr. Dadu experienced no ceiling effect with Mounjaro, unlike her experience with Victoza.
04. Are IV drips necessary while on Mounjaro?
They aren't mandatory, but many patients use them to support nutrition and reduce potential side effects.
05. Can Mounjaro help with skin pigmentation issues?
Yes, some patients have seen improvement in acanthosis nigricans even after just a couple of doses.
06. Is doctor supervision really necessary for Mounjaro?
Yes, regular blood tests and monitoring are essential to ensure safety and optimize results.
07. How long should someone stay on Mounjaro?
Duration varies by individual goals; the aim is achieving target weight safely, not rushing to the highest dose.
08. Can Mounjaro be stopped after reaching target weight?
Yes, with gradual tapering and continued healthy lifestyle habits to maintain results.

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